Context: Researchers at Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST), Srinagar, have created India’s first gene-edited sheep.
India’s First Gene Edited SHEEP
- Utilised CRISPR-Cas9 technology to edit the myostatin gene, which regulates muscle growth.
- Result: 30% increase in muscle mass in sheep.
- Myostatin disruption leads to higher muscle development, similar to the Exel breed (a European sheep breed known for high muscle mass).
- Can be used to:
- Improve meat yield in livestock.
- Create disease-resistant animals.
- Assist in twinning and other reproductive advantages.
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What is Myostatin?
- Myostatin is a protein that is produced by the MSTN (or GDF8) gene.
- It acts as a negative regulator of muscle growth.
- Inhibits muscle cell growth and differentiation.